Case Data:  Glioblastoma (GBM)

Axial T1-post contrast (Ax SE T1 POST FC) 1.5T MRI of the brain of a 64-yr old male patient with glioblastoma (GBM) treated with BXQ-350. GBM was first diagnosed in 2013 and previously treated with surgery, chemotherapy and radiation. Measurable lesion reduction over time is apparent in the anterior corpus callosum and frontal lobe, with those bordering the ventricle.

The brain of a 64-yr old male patient with glioblastoma (GBM) treated with BXQ-350

Red Arrows indicate the initial target lesion that decreased in size while on study

Blue Arrows indicate new area of enhancement

Note: Surgery in May, 2018 revealed significant treatment effect with only trace tumor cells present. As of September, 2019 patient continues on study having completed 3 years in the trial.

Case Data:  Colorectal Cancer

40 year old female with stage 4 colorectal cancer – six prior treatment lines

Before: 40 year old female with stage 4 colorectal cancer

PET/CT Scan 10/31/2016

Before starting BXQ-350 treatment

After: 40 year old female with stage 4 colorectal cancer

PET/CT Scan 04/23/2018

After 1 year on Phase I  Safety Trial with BXQ-350 treatment